Archive for the ‘obesity’ Category

Doctors Sometimes Add to Misperceptions about Being Overweight

Thursday, March 31st, 2011

A great many of us perceive our weight to be in the normal range when in fact we are overweight or even seriously obese. And in many cases, our doctors are not helping correct the misperception. Studies show that 55% of overweight people (BMI 26-29.9) and 33% of obese people (BMI 30+) have never been told by a doctor that they are overweight.

Twenty percent of obese patients who have never had this conversation with their doctor described themselves as “not overweight” compared to just 3% of those whose doctors had spoken to them about their weight.  A similar study of overweight patients found that 23% of females and 48% of males considered their weight to be “just right” despite their heightened risks of diabetes and many other diseases stemming from all the extra pounds of body weight.

Physicians and other health care providers do serve an important role in communicating when an individual is overweight or obese because it is such an important health matter and one that every person needs to understand so that they may begin doing something about it.

FATTY ACIDS AND LIPOPROTEIN LIPASE (LPL) MAY HOLD KEY TO OBESITY IN THE BRAIN

Saturday, February 12th, 2011

Basic science researchers continue to examine the molecular and biochemical structure that controls metabolism.  Researchers are unlocking some of the mysteries as to the biochemical basis of obesity.  In one recent such study released in January of 2011, Dr. Hong Wang and a team of researchers from the University of Colorado School of medicine in collaboration with other institutions described a study of fatty acid metabolism in brain cells.  Their research involves a specific type of genetically modified mouse that has an impaired lipoprotein lipase enzyme in the brain cells or neurons.  Lipoprotein lipase is an important enzyme in the neurons that allows the breakdown of fats into its building blocks and allows the free fatty acids to be delivered to the brain.  What these researchers discovered was that impairing that enzymatic process led to the mice eating more and becoming more sedentary, and then becoming obese.

The area of the brain that was most affected appeared to be hypothalamus, one of the central regulatory centers of the brain.  It is hypothesized that the lipoprotein lipase allows delivery of fatty acids to these important brain cells in the sensitive hypothalamic brain nuclei that provide important signals to regulate body metabolism, body energy expenditure and body mass.

While these studies are at the level of the laboratory and the animal neurons, they appear to hold important clues for the future of improved understanding of metabolism and obesity.  One day it is hoped such research will lead to pharmaceutical interventions, which might promote improved delivery of free fatty acids to the hypothalamus and serve to re-institute proper metabolism and energy balance in people who are losing it and gaining weight.


Dr. Kent Sasse, Medical Director | 75 Pringle Way Suite 804 Reno, NV 89502 | Phone: 775-829-7999

Dr. Kent Sasse serves the entire city of Reno and all the surrounding areas. Dr. Sasse is one of the nation's foremost medical weight loss and bariatric surgical experts.
Dr. Sasse has educated patients about food nutrition and weight loss for many years.

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